If you're not a VCDS guru, you can throw some parts at it.
In order of cost, cheapest first:-
Spark plugs - dealer NGKs, or NGK BKR7EIX. Both the same heat grade and gap, but these TFSIs seem to like the Iridiums.
Coils - A set of red ones from AKS are <£100. Dealer black ones are ~£40 each. Both the same. Reds just cheaper.
Injectors - Do all 4. It's a waste of time pulling the intake off to replace only 1. The other 3 will follow suit soon after.
If you do have access to VCDS, a persistent misfire will be fault coded if the detection count meets or exceeds it's limit. Or you can fire up the live counter channels 1 - 4. If the ECU detects a cylinder not contributing (crank speed not increasing on the power stroke) it will flag it.
Generally with injectors, idle and part throttle can feel lumpy but smoothes out under acceleration.
With dying coils, it usually misses under load, usually from cold at 1/2 throttle. When gone completely, the miss will be permanent.
If none of the above, compression test it. You should see ~14 bar across all 4 on a healthy engine. If one cylinder is much less than the other 3, there's your problem. Busted ring land or a burned out exhaust valve. Usually the former on remapped engines.
Seafoam and other spray in snake oils do absolutely nothing on old engines, let alone modern DI engines.